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REVOLUTION

(selemectin)

page.  To return to the main/index page, you may either use your "back" browser or click here:  http://rimadyldeath.com

The music for this page is "How Insensitive"



According to Pfizer at: http://www.revolution4dogs.com/content.asp?country=US&lang=EN&drug=RV&species=CN&sec=000

"Revolution (selamectin) is the safe, simple way to protect your dog from heartworms, fleas and other harmful parasites. Protecting pets from harm is one of the important promises that bonds people and their pets."
 
Per the FDA/CVM's ADE reports at http://www.fda.gov/cvm/ade_cum.htm and
(selemectin)  from: http://www.fda.gov/cvm/Documents/ade_web_rpts_SZ.pdf:
 
This page is starting out with the biggest report, which is then followed by additional smaller reports which are numbered and appear below this one.  The ONLY thing I have done with the FDA/CVM's ADE [Adverse Drug Event] reports is to put the symptoms/conditions in alphabetical order (in some instances they are additionally grouped by body system, such as "eyes", "heart", "lab tests", etc.) and provide medical terminology definitions, all of which are from Medline at:  http://www.nlm.nih.gov/medlineplus/mplusdictionary.html unless otherwise indicated.
 
REPORT DATE: 5/02/05
 
Report Title "Selemectin, TOPICAL, DOG"
 
Reviews:      7661
Treated:      9737
Reacted:      9545 (NOTE: as ADE's are filed to report reactions, it is not known how there were 192 dogs who allegedly did not have a reaction when treated; possibly the "Arthur Anderson Principles of Accounting were used here)
Died:           223 
 
KNOWN symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
 
ABORTION
ADIPSIA
  - loss of thirst ; also : abnormal and especially prolonged abstinence from the intake of fluids
AGGRESSION
/TOID - 1: hypersensitivity (as to foreign proteins or drugs) resulting from sensitization following prior contact with the causative agent  2 : ANAPHYLACTIC SHOCK - an often severe and sometimes fatal systemic reaction in a susceptible individual upon a second exposure to a specific antigen (as wasp venom or penicillin) after previous sensitization that is characterized especially by respiratory symptoms, fainting, itching, and hives
ANEMIA
ANEMIA, AUTOIMMUNE HEM
ANEMIA, HEINZ BODY
ANEMIA, HEMOLYTIC
ANEMIA, REGEN
ANEMIA, SPHERO
ANESTRUS
- the period of sexual quiescence between two periods of sexual activity in cyclically breeding mammals
ANOREXIA - loss of appetite especially when prolonged
APNEA - transient cessation of respiration whether normal (as in hibernating animals) or abnormal (as that caused by certain drugs)
APPREHENSION
ARTHRITIS
ASCITES
- accumulation of serous fluid in the spaces between tissues and organs in the cavity of the abdomen -- called also hydroperitoneum
ATAXIA - an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders
ATROPHY, MUSCLE(S) - decrease in size or wasting away of a body part or tissue ; also : arrested development or loss of a part or organ incidental to the normal development or life of an animal or plant
AZOTEMIA - an excess of nitrogenous bodies in the blood as a result of kidney insufficiency
BEHAVIOR DISORDER
BIRTH DEFECT(S)
BIRTH DEFECT(S), TORSO
BITING/CHEWING
BLEEDING:
    BLD  unspecified site
    BLD, ABDOMEN
    BLD, ANUS
    BLD, EAR(S)
    BLD (ECCHYMOSES)
- the escape of blood into the tissues from ruptured blood vessels marked by a livid black-and-blue or purple spot or area ; also : the discoloration so caused -- compare PETECHIA 
   BLD(HEMATOMA) - a mass of usually clotted blood that forms in a tissue, organ, or body space as a result of a broken blood vessel 
   BLD, LUNG(S)/TRACHEA
   BLD, MOUTH/LIP(S)
   BLD, SCLERA
   BLD, SKIN
   BLD, URINE
BLINDNESS
BLINDNESS, PARTIAL
BLINDNESS, TEMP
BLOAT
BORBORYGMI
- a rumbling sound made by the movement of gas in the intestine
BREATHING ABN
BREATHING, DIFFICULT
CACHEXIA
- general physical wasting and malnutrition usually associated with chronic disease
CHOKING
CIRCLING
CNS DISORDER
- abbreviation: central nervous system
CNS INFARCT - an area of necrosis in a tissue or organ resulting from obstruction of the local circulation by a thrombus or embolus
COLITIS - inflammation of the colon
COLLAPSE
CONFUSION

CONGESTION
  unspecified site
CONGESTION, EAR(S)
CONGESTION, LUNG(S)
CONGESTION, MUCOUS MEM
CONGESTION, NOSE
CONGESTION, TONGUE
CONSTIPATION
CONVULSION(S)
COOMBS TEST POS
- an agglutination test used to detect proteins and especially antibodies on the surface of red blood cells
COUGHING
CSF ABN
- COLONY-STIMULATING FACTOR:  any of several glycoproteins that promote the differentiation of stem cells especially into blood granulocytes and macrophages and that stimulate their proliferation into colonies in culture
CYANOSIS - a bluish or purplish discoloration (as of skin) due to deficient oxygenation of the blood
CYSTITIS - inflammation of the urinary bladder
DEAFNESS
DEAFNESS, PARTIAL
DEAFNESS, TEMP
DEFECATION ABN
DEHYDRATION
DEPRESSION/LETHARGY
DESTRUCTIVENESS
DISCOMFORT, MOUTH/LIP(S)
DIFFICULTY RISING
DIARRHEA
DIARRHEA, BLOODY
DIARRHEA, MILD
DIARRHEA, MUCOID
DIARRHEA, PROJECTILE
DIARRHEA, SEVERE
DIARRHEA, WATERY
DIC
- per the Merck Veterinary Manual online at:   http://www.merckvetmanual.com, I was not able to find "DIC", but the search engine provided 14 "articles" for that search, the first of which is: "Acquired Coagulation Protein Disorders" and states: "Most coagulation proteins are produced primarily in the liver. Therefore, liver disease characterized by necrosis, inflammation, neoplasia, or cirrhosis often is associated with decreased production of coagulation proteins, particularly Factors VII, IX, X, and XI." and refers on to: "(see rodenticide poisoning)". A search of: http://www.medterms.com using "DIC" provided: "3 articles" for search keyword or phrase "DIC", the titles of which are: "Leukemia in the Family", "Acute promyelocytic leukemia" and "APL" which provides a potential definition of "DIC" as "APL is consistently associated with a disorder that resembles (but is not identical to) disseminated intravascular coagulation (DIC). "There is in APL a pronounced tendency to hemorrhage (bleeding). The bleeding can manifest itself as petechiae (little bleeding spots in the skin or elsewhere), small ecchymosis (bruises), epistaxis (nose bleeds), bleeding in the mouth, hematuria (blood in the urine), bleeding from venipuncture and bone marrow sites. . . " so apparently the "translation" of "DIC" is disseminated intravascular coagulation.  
DILITATION, ESOPHAGUS - no such word;  
dilatation: the condition of being stretched beyond normal dimensions especially as a result of overwork or disease or of abnormal relaxation <dilatation of the heart> <dilatation of the stomach>
DISCHARGE, NOSE
DISCOMFORT
DISSOCIATION
- 1. the act or process of dissociating : the state of being dissociated: as a : the process by which a chemical combination breaks up into simpler constituents ; especially : one that results from the action of energy (as heat) on a gas or of a solvent on a dissolved substance b : the separation of whole segments of the personality (as in multiple personality) or of discrete mental processes (as in the schizophrenias) from the mainstream of consciousness or of behavior with loss of integrated awareness and autonomous functioning of the separated segments or parts; 2 : the process by which some biological stocks (as of certain bacteria) differentiate into two or more distinct and relatively permanent strains ; also : such a strain
DISTENTION, ABDOMEN
DISTRESS
DISTRESS, RESP
DIZZINESS
DYSMETRIA
- impaired ability to estimate distance in muscular action
DYSPNEA - difficult or labored respiration
DYSURIA - difficult or painful discharge of urine
EAR DISORDER
ECG ABN
- abbreviation: electrocardiogram
EDEMA
  unspecified site - an abnormal excess accumulation of serous fluid in connective tissue or in a serous cavity -- called also dropsy
EDEMA, HEAD/FACE
EDEMA, LIMB(S)
EDEMA, LUNG(S)/TRACHEA
EDEMA, NECK
EDEMA, PREPUCE -
FORESKIN ; also : a similar fold investing the clitoris
EFFUSION, PLEURAL - 1 : an exudation of fluid from the blood or lymph into a pleural cavity  2 : an exudate in a pleural cavity ELECTROLYTE DISORDER
ENLARGEMENT(S)
  unspecified site
ENLARGEMENT, LYMPH NOD
EPISTAXIS
NOSEBLEED
ESTRUS BEHAVIOR
EYES:
    ABRASION, CORNEA(S)
    BLD, EYE(S)
    BLEPHAROSPASM
- spasmodic winking from involuntary contraction of the orbicularis oculi muscle of the eyelids
   C ATARACT(S)
   CONGESTION, EYE(S)/LID
   CONJUNCTIVITIS
- inflammation of the conjunctiva 
   DISCHARGE, EYE(S)/LID(S)
   EDEMA, EYE(S)/LID(S)
   EPIPHORA
- a watering of the eyes due to excessive secretion of tears or to obstruction of the lacrimal passages 
   HYPHEMA - a hemorrhage in the anterior chamber of the eye 
   IRRITATION, EYE(S)/LID
   MIOSIS
- excessive smallness or contraction of the pupil of the eye 
   MYDRIASIS - excessive or prolonged dilation of the pupil of the eye 
   NYSTAGMUS - a rapid involuntary oscillation of the eyeballs occurring normally with dizziness during and after bodily rotation or abnormally after injuries (as to the cerebellum or the vestibule of the ear) 
   NYSTAGMUS, HORIZONTAL
   OPACITY, CORNEA(S)
   OTITIS
- inflammation of the ear 
   PROLAPSE, THIRD EYELID - Hypertrophy and prolapse of the gland of the nictitating membrane (cherry eye) is common in young dogs. Prolapsed gland of  nictitating membrane, dog In the acute stage, the red mass swells and protrudes over the leading margin of the nictitans, and there is a mucopurulent discharge. Although the swelling may recede for short periods, it eventually often remains prolapsed.
   PROTRUSION, EYE(S)
   PRURITIS, EYE(S)
- localized or generalized itching due to irritation of sensory nerve endings from organic or psychogenic causes : ITCH 
   PUPIL(S), AREFLEXIA - absence of reflexes 
   STRABISMUS - inability of one eye to attain binocular vision with the other because of imbalance of the muscles of the eyeball -- called also heterotropia, squint 
   SWELLING, EYE(S)/LID(S
   UVEITIS
- inflammation of the uvea. One entry found for uvea: the middle layer of the eye consisting of the iris and ciliary body together with the choroid coat -- called also vascular tunic 
    VISION DISORDER
EXERCISE INTOLERANCE
FERTILITY, LACK OF
FEVER, BODY
FLATULENCE
FLY BITING - from Merck Veterinary Manual online: A specific type of seizure known as temporal lobe epilepsy appears to be familial in Cavalier King Charles Spaniels and is characterized by behavioral manifestations such as fly biting 
FROTH, MOUTH/LIP(S)
GAGGING
GASTRITIS
- inflammation especially of the mucous membrane of the stomach
GASTROENTERITIS - inflammation of the lining membrane of the stomach and the intestines
GI, ABNORMAL
GINGIVITIS - inflammation of the gums
GRINDING TEETH
HALLUCINATION
HEAD BOBBING
HEAD TILT
HEART:
   ARREST, HEART
   ARRHYTHMIA
- an alteration in rhythm of the heartbeat either in time or force 
   BRADYCARDIA - relatively slow heart action whether physiological or pathological -- compare TACHYCARDIA 
   CARDIOMEGALY - enlargement of the heart 
   ECG ABN - abbreviation: electrocardiogram 
   EMBOLUS - an abnormal particle (as an air bubble) circulating in the blood -- compare THROMBUS 
   HEART DISORDER
   MURMUR, HEART
   PRESSURE HI, BLD
   PRESSURE LO, BLD
   REGURGITATION
- an act of regurgitating ; especially : the backward flow of blood through a defective heart valve -- see AORTIC REGURGITATION : leakage of blood from the aorta back into the left ventricle during diastole because of failure of an aortic valve to close properly -- called also aortic incompetence, aortic insufficiency, Corrigan's disease 
   TACHYCARDIA - relatively rapid heart action whether physiological (as after exercise) or pathological 
   THROMBUS - a clot of blood formed within a blood vessel and remaining attached to its place of origin -- compare EMBOLUS
HEMATOCHEZIA - the passage of blood in the feces -- compare MELENA
HEPATOMEGALY - enlargement of the liver
HIDING
HYPERACTIVITY
HYPERESTHESIA
- unusual or pathological sensitivity of the skin or of a particular sense to stimulation <tactile hyperesthesia of the leg>
HYPERPNEA - abnormally rapid or deep breathing
HYPERTONIA - HYPERTONICITY : the quality or state of being hypertonic: exhibiting excessive tone or tension  
HYPERSALIVATION - excessive salivation (drooling)
HYPERSENSITIVE, SOUND
HYPOADRENOCORTICISM
- abnormally decreased activity of the adrenal cortex (as in Addison's disease)
HYPOTHERMIA - subnormal temperature of the body <hypothermia, defined as temperature under 36.6C
HYPOTHERMIA, BODY
ICTERUS
- JAUNDICE : 1 : a yellowish pigmentation of the skin, tissues, and certain body fluids caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states) -- called also icterus  2 : any disease or abnormal condition (as hepatitis A or leptospirosis) that is characterized by jaundice -- called also icterus
ICTERUS, BODY
ICTERUS, SERUM
ILL
IMMUNE DISORDER
IMMUNOSUPPRESSION
- suppression (as by drugs) of natural immune responses
INCONTINENCE - inability of the body to control the evacuative functions
INCONTINENCE, FECAL
INCONTINENCE, URINARY
INFARCT
- an area of necrosis in a tissue or organ resulting from obstruction of the local circulation by a thrombus or embolus
INEFFECT
INEFFECT, EAR MITES
INEFFECT, ECTOPARASITE
INEFFECT, FLEAS
INEFFECT, HOOKS
INEFFECT, HOOKS PREVEN
INEFFECT, HW ADULTS
INEFFECT, HW ANTIGEN
INEFFECT, HW LARVAE
INEFFECT,  HW MICROFILA
INEFFECT, LOSS OF EFFE
INEFFECT, MITES
INEFFECT, PARASITE
INEFFECT, SARCOPTES MITES
INEFFECT, STRONGYLES
INEFFECT, TICKS
INEFFECT, WHIPS PREVEN
INFECTION
  unspecified site
INFECTION, FEET/DIGIT(
INFECTION, URINARY TRA
INFLAM
  unspecified site
INSOMNIA
IRRITATION
  unspecified site
IRRITATION, EAR(S)
IRRITATION, ESOPHAGUS
IRRITATION, PERINEUM
KIDNEY FAILURE
LAB/BLOOD:
    ALBUMIN HI, BLD
   ALBUMIN LO, BLD
   ALK PHOS HI, BLD
   AMYLASE HI, BLD
   BANDS HI, BLD
   BILIRUBIN(TOT) HI, BLD
   
BILE ACIDS HI, BLD
   BUN HI, BLD
   BUN LO, BLD
   CA HI, BLD
   CA LO, BLD
   CHEMISTRY ABN
   CHLORIDE LO, BLD
   CHOLESTEROL HI, BLD
   CO2 HI, BLD
   COAGULATION DISORDER
   CPK HI, BLD
   CREATININE HI, BLD
   CREATININE LO, BLD
   EOSINOS HI, BLD
   FE LO, BLD
   FIBRINOGEN LO, BLD
   GGT HI, BLD
   GLOBULIN HI, BLD
   GLOBULIN LO, BLD
   GLUCOSE HI, BLD
   GLUCOSE LO, BLD
   HCO3 HI, BLD
   K HI, BLD
   K LO, BLD
   KIDNEY VALUES HI, BLD
   LIPASE HI, BLD
   LIVER ENZYMES HI, BLD
   LYMPHS HI, BLD
   LYMPHS LO, BLD
   MONOS HI, BLD
   NA HI, BLD
   NA LO, BLD
   P HI, BLD
   PANCREAS ENZYMES HI, B
   PLATELETS HI, BLD
   PLATELETS LO, BLD
   PROTEIN(TOT) HI, BLD
   PROTEIN(TOT) LO, BLD
   PTT PROLONGED, BLD
   RBC, NUCLEATED
   RETICULOCYTES HI, BLD
   RETICULOCYTES LO, BLD
   SEGS HI, BLD
   SEGS LO, BLD
   SGOT/AST HI, BLD
   SGPT/ALT HI, BLD
   THYROID HORMONE(S) LO
   TRIGLYCERIDES HI, BLD
   WBC HI, BLD
   WBC LO, BLD
LAB/URINE
:
   ABN COLOR, URINE
   ALKALINE URINE
   BILIRUBIN, URINE
   BLD, URINE

   CALCULI, BLADDER
   CALCULI, URINE
   CRYSTALS, URINE
   GLUCOSE, URINE
   HEMOGLOBIN, URINE
   MICROORANISMS, URINE
   PROTEIN, URINE
   SPEC GRAVITY LO, URINE
   WBC, URINE
LABOR, PREMATURE
LAMENESS
LICKING
LICKING, FEET/DIGIT(S)
LIVER DISORDER
LIVER FAILURE
LOCOMOTION DISORDER
MASS
  unspecified site
MASS, ABDOMEN
MORIBUND
- being in the state of dying : approaching death <in the moribund patient deepening stupor and coma are the usual preludes to death
MUCOUS MEMBR, ABN COLO
MYOSITIS
- muscular discomfort or pain from infection or an unknown cause
NAUSEA
NECROSIS
  unspecified site - death of living tissue ; specifically : death of a portion of tissue differentially affected by local injury (as loss of blood supply, corrosion, burning, or the local lesion of a disease)
NEOPLASM  unspecified site - a new growth of tissue serving no physiological function : TUMOR -- compare CANCER : 1 : a malignant tumor of potentially unlimited growth that expands locally by invasion and systemically by metastasis -- compare CARCINOMA, SARCOMA; NEOPLASM, TUMOR  2 : an abnormal state marked by a cancer
NEOPLASM, LIVER
NEOPLASM, LYMPH NODE(S
NEOPLASM, MULT SITES
NEPHRITIS
- acute or chronic inflammation of the kidney affecting the structure (as of the glomerulus or parenchyma) and caused by infection, a degenerative process, or vascular disease
NERVOUSNESS
NEUROLOGICAL DISORDER
NO SIGNS
NOSE ABN
ODOR
ODOR, MOUTH
OPISTHOTONOS
- a condition of spasm of the muscles of the back, causing the head and lower limbs to bend backward and the trunk to arch forward
PACING
PAIN
PAIN, ABDOMEN
PAIN,  BACK
PAIN, HEAD/FACE
PAIN,  HIND LIMB(S)
PAIN, JOINT(S)
PAIN, MOUTH/LIP(S)
PAIN, MUSCLE(S)
PAIN, NECK
PAIN, SPINAL
PALLOR
PALLOR, MUCOUS MEMBRAN
PANCREATITIS
- inflammation of the pancreas
PARALYSIS - complete or partial loss of function especially when involving the power of motion or of sensation in any part of the body
PARALYSIS, ALL LIMBS
PARALYSIS, FACIAL NERV
PARALYSIS, HIND LIMB(S
PARESIS
- 1 : slight or partial paralysis  2 : GENERAL PARESIS
 insanity caused by syphilitic alteration of the brain that leads to dementia and paralysis -- called also dementia paralytica, general paralysis of the insane
PARESIS, FORE LIMB(S)
PARESIS, HIND LIMB(S)
PAWING
PR-BLD VESSEL(S), LESI
PR-BONE MARROW, LESION
PR-CEREBRUM, LESION(S)
PD-COLOR, ABN
PD-ODOR, ABN
PD-POTENCY, HI
PD-POTENCY, LO
PD-PRODUCT DEFECT
PD-SOLUTION, ABN
PD-UNDERFILL, PACKAGE
PD-UNDERFILL, TUBE(S)
PD-UNKNOWN
PD-TUBE(S), ABN
PD-TUBE(S), LEAKING
PD-UNDERFILL, VIAL(S)
PERITONITIS
- inflammation of the peritoneum
PHALLITIS - No entries found that match PHALLITIS; One entry found for phallus: PENIS
PNEUMONIA
POLLAKIURIA
- abnormally frequent urination
POLYCYTHEMIA - a condition marked by an abnormal increase in the number of circulating red blood cells
POLYCYTHEMIA(RELATIVE)
POLYDIPSIA
- excessive or abnormal thirst
POLYPNEA - rapid or panting respiration
POLYURIA - excessive secretion of urine
PROPRIOCEPTIVE DISORDE - activated by, relating to, or being stimuli arising within the organism <proprioceptive reflexes> <proprioceptive feedback>: proprioceptive neuromuscular facilitation: a method of stretching muscles to maximize their flexibility that is often performed with a partner or trainer and that involves a series of contractions and relaxations with enforced stretching during the relaxation phase -- abbreviation PNF
PR-APP SITE, LESION(S)
PR-FETUS, LESION(S)
PR-GI, LESION(S)
PR-GI, PARASITISM
PR-HEARTWORM DISEASE
PR-INTEST, LESION(S)
PR-KIDNEY(S), LESION(S
PR-LIVER, LESION(S)
PR-LUNG(S), EDEMA
PR-LUNG(S), LESION(S)
PR-LYMPH NODE(S), LESI
PR-MENINGES, LESION(S)
PR-MULT SITES, BLD
PR-MULT SITES, CONGEST
PR-MULT SITES, LESION(S)
PR-PANCREAS, LESION(S)
PR-PERITONEAL EFFUSION
PR-SKIN, LESION(S)
PR-SM INTEST, LESION(S
PR-SPLEEN, LESION(S)
PR-STOMACH, LESION(S)
PR-TESTES, LESION(S)
PR-THYMUS, LESION(S)
PR-TRACHEA, LESION(S)
PRURITIS
- No entries found that match PRURITIS: pruritus: localized or generalized itching due to irritation of sensory nerve endings from organic or psychogenic causes : ITCH
PRURITIS, EAR(S)
PRURITIS, FEET/DIGIT(S
PRURITIS, TAIL
RADIOGRAPH(S) ABN
RECUMBENCY
- the state of leaning, resting, or reclining ; also : a recumbent position <emphasized that recumbency may ... be harmful to the patient who is acutely ill with cardiac disease
REFLEX(ES) ABN
RELUCTANT TO MOVE
RESIDUE, URINE
ROLLING
SEDATION
SHAKING
SHAKING, HEAD/FACE
SHOCK
- 1 : a sudden or violent disturbance in the mental or emotional faculties  2 : a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery <the patient was admitted to the hospital in shock3 : sudden stimulation of the nerves or convulsive contraction of the muscles accompanied by a feeling of concussion that is caused by the discharge through the animal body of electricity from a charged source
SLOUGH
  unspecified location - dead tissue separating from living tissue ; especially : a mass of dead tissue separating from an ulcer
SLOUGH, EAR(S)
SLOUGH, FEET/DIGIT(S)
SKIN:
    ABSCESS, SKIN
    ALOPECIA - loss of hair, wool, or feathers : BALDNESS 
    APPLICATION SITE ABNORMAL
    APPLICATION SITE ALOPECIA
    APPLICATION SITE EDEMA
    APPLICATION SITE ERYTHEMA
- abnormal redness of the skin due to capillary congestion (as in inflammation
    APPLICATION SITE HAIR, ABN
    APPLICATION SITE HAIR, ABN COLOR
    APPLICATION SITE INFLAM
    APPLICATION SITE LESION(S)
    APPLICATION SITE MASS
    APPLICATION SITE PAIN
    APPLICATION SITE PRURITIS
    APPLICATION SITE SKIN, DRY
    APPLICATION SITE SWELLING
    BLD(PETECHIAE)
- a minute reddish or purplish spot containing blood that appears in skin or mucous membrane especially in some infectious diseases (as typhoid fever)
    CELLULITIS - diffuse and especially subcutaneous inflammation of connective tissue 
    CONGESTION, SKIN - an excessive accumulation especially of blood in the blood vessels of an organ or part whether natural or artificially induced (as for therapeutic purpose)
    DERMATITIS, MOIST - inflammation of the skin
    DRY, SKIN
    ENLARGEMENT(S), SKIN
    ERUPTION(S)
- 1 : an act, process, or instance of erupting <the eruption of the tooth from the gum> ; specifically : the breaking out of an exanthem or enanthem on the skin or mucous membrane (as in measles)  2 : something produced by an act or process of erupting: as a : the condition of the skin or mucous membrane caused by erupting b : one of the lesions (as a pustule) constituting this condition 
    ERYTHEMA MULTIFORME - a skin disease characterized by papular or vesicular lesions and reddening or discoloration of the skin often in concentric zones about the lesions 
    G-HAIR, ABN COLOR
    HAIR, ABN
    HAIR, ABN COLOR
    HAIR, SHEDDING
    HYPERKERATOSIS
- hypertrophy of the stratum corneum layer of the skin
    HYPERPIGMENTATION, SKI - excess pigmentation in a bodily part or tissue (as the skin) <brown hyperpigmentation with accentuation in sun-exposed areas 
    INFECTION, SKIN
    INFLAM, SKIN
    INJ SITE MASS
    IRRITATION, SKIN
    LESION(S), SKIN
    LEUKODERMA
- a skin abnormality that is characterized by a usually congenital lack of pigment in spots or bands and produces a patchy whiteness 
    MASS, SKIN
    MELENA
- the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum -- compare HEMATOCHEZIA 
    NEOPLASM, SKIN - a new growth of tissue serving no physiological function : TUMOR -- compare CANCER 
    PAPULE(S) - a small solid usually conical elevation of the skin caused by inflammation, accumulated secretion, or hypertrophy of tissue elements 
    PUSTULE(S) - 1 : a small circumscribed elevation of the skin containing pus and having an inflamed base  2 : a small often distinctively colored elevation or spot resembling a blister or pimple 
    RASH
    RESIDUE, APPLICATION SITE
    SCALE(S), SKIN
    SEBORRHEA - abnormally increased secretion and discharge of sebum producing an oily appearance of the skin and the formation of greasy scales 
    SKIN, CRUST(S)
    SKIN DISORDER
    SKIN, DRY
    SKIN, NECROSIS
    SKIN, SCAB(S)
    SLOUGH, SKIN
    VESICLE(S)/BULLAE, SKI
- 1 a : a membranous and usually fluid-filled pouch (as a cyst, vacuole, or cell) in a plant or animal b : SYNAPTIC VESICLE
2 : a small abnormal elevation of the outer layer of skin enclosing a watery liquid : BLISTER  3 : a pocket of embryonic tissue that is the beginning of an organ -- see BRAIN VESICLE, OPTIC VESICLE 
    ULCER(S), SKIN
SNEEZING
SOMNOLENCE
- the quality or state of being drowsy
SORE(S)
unspecified location
SOUND ABN, RESPIRATORY
SPASM
SPERM ABN
SPLENOMEGALY
- abnormal enlargement of the spleen
STAGGERING
STARING
STIFFNESS
STIFFNESS, HIND LIMB(S
STIFFNESS, LIMB(S)
STIFFNESS, NECK
STOOL ABN
STOOL, MUCOID
STRAINING
STRANGURIA
- No entries found that match STRANGURIA- One entry found for strangurya slow and painful discharge of urine drop by drop produced by spasmodic muscular contraction of the urethra and bladder  
STUMBLING
STUPOR
- a condition of greatly dulled or completely suspended sense or sensibility <a drunken stupor> ; specifically : a chiefly mental condition marked by absence of spontaneous movement, greatly diminished responsiveness to stimulation, and usually impaired consciousness
SWEATING
SWELLING, ADM SITE
SWELLING, EAR(S)
SWELLING, FEET/DIGIT(S
SWELLING, HEAD/FACE
SWELLING, JOINT(S)
SWELLING, MOUTH/LIP(S)
SWELLING, NECK
SWELLING, MULT SITES
SWELLING, PHARYNX/THRO
SWELLING, PREPUCE
SWELLING, TONGUE
SYNCOPE
- loss of consciousness resulting from insufficient blood flow to the brain : FAINT
TAIL DISORDER
TASTE ABNORMALITY
TEETH, ABN
TENESMUS, RECTAL
- a distressing but ineffectual urge to evacuate the rectum or urinary bladder
THRASHING/PADDLING
TONGUE, ABN
TORTICOLLIS
- a twisting of the neck to one side that results in abnormal carriage of the head and is usually caused by muscle spasms -- called also wryneck
TOX - No entries found that match TOX. One entry found for toxicity: the quality, state, or relative degree of being toxic or poisonous
TREMBLING
TREMBLING, FACE
TWITCH
ULCER(S
unspecified site
ULCER(S), EAR(S)
ULCER(S), FEET/DIGIT(S
ULCER(S), MOUTH/LIP(S)
ULCER(S), STOMACH
UNCONSCIOUS
UREMIA
- 1 : accumulation in the blood of constituents normally eliminated in the urine that produces a severe toxic condition and usually occurs in severe kidney disease  2 : the toxic bodily condition associated with uremia <the patient was in uremia>
URINATION
URINATION ABN
URTICARIA
- HIVES an urticarial wheal
US ABN - No entries found that match US
VASCULITIS - inflammation of a blood or lymph vessel -- called also angiitis
VESTIBULAR DISORDER - 1 : of or relating to the vestibule of the inner ear, the vestibular apparatus, the vestibular nerve, or the labyrinthine sense <vestibular impulses>  2 : lying within or facing the vestibule of the mouth <the vestibular surface of a tooth>
VOCALIZATION
VOLVULUS, INTESTINE
- a twisting of the intestine upon itself that causes obstruction
VOMITING
VOMITING, BLOODY
VOMITING   ROUNDWORMS
VOMITING,  SEVERE
VOMITING, UNPRODUCTIVE
WEAKNESS
WEIGHT INCREASE
WEIGHT LOSS
WHEEZING

 
#1 REPORT DATE:  5/02/05
 
Report Title "Selamectin, MISSING DOG"
 
Reviews:   5
Treated:    5
Reacted:   5
Died:          0
 
Symptoms/conditions caused by and/or associated with Revolution administration:
 
ANOREXIA
APPLICATION SITE ALOPECIA
APPLICATION SITE HAIR, ABN COLOR
DIARRHEA
HAIR, ABN COLOR
INEFFECT
RECUMBENCY
TREMBLING
VOMITING
 

#2 REPORT DATE: 5/02/05
 
Another "MISSING DOG" Report [NOTE: it is not known whether these are the same "missing dogs" or not, as it's a separate report]
 
Reviews:  5
Treated:   5
Reacted:  5
Died:         0
 
Symptoms/conditions caused by and/or associated with Revolution administration:
 
ANOREXIA
APPLICATION SITE ALOPECIA
APPLICATION SITE HAIR, ABN COLORDIARRHEA
HAIR, ABN COLOR
INEFFECT
RECUMBENCY
TREMBLING
VOMITING


#3 REPORT DATE: 5/02/05:
 
This report is entitled "Selamectin, NOT APPLICABLE, DOG"
 
Reviews:     7
Treated:    64
Reacted:   64
Died:            0
 
Symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
INEFFECT, FLEAS                                72%
INEFFECT, EAR MITES                       13%
INEFFECT, SARCOPTES MITES         8%
INEFFECT, TICKS                                    5%
PD-SOLUTION, ABN                                 2%
PD-UNDERFILL, TUBE(S)                       2%
 

#4 REPORT DATE: 5/02/05
 
Report titled "Selamectin, OPTHALMIC, DOG", apparently indicating this was put into the dog's eyes.
 
Reviews:   1
Treated:    1
Reacted:   1
Died:          0
 
Symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
EDEMA, EYE(S)/LID(S)             100%
ULCER(S), CORNEA(S)              100%
 

#5 REPORT DATE: 5/02/05
 
Report  titled: "Selamectin, ORAL, DOG"
 
Reviews:     56
Treated:    125
Reacted:    125
Died:               4
 
Symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
ACCIDENTAL EXPOSURE
ANAPHYLAXIS/TOID
ANOREXIA
ATAXIA
CNS INFARCT
COLLAPSE
CONVULSION(S)
DEPRESSION/LETHARGY
DIARRHEA
DIARRHEA, MILD
DIZZINESS
DYSPNEA
EDEMA
EDEMA, HEAD/FACE
FEVER, BODY
HEMATOCHEZIA
HYPERACTIVITY
HYPERPNEA
HYPERSALIVATION
INEFFECT, FLEAS
INEFFECT, HW LARVAE  (65%)
INEFFECT, TICKS
INTERACTION, DRUG(S)
LAB TESTS/BLOOD:
    ALBUMIN LO, BLD
    CPK HI, BLD
    GLUCOSE LO, BLD
    LIVER ENZYMES HI, BLD
    P HI, BLD
    SEGS HI, BLD
    WBC HI, BLD
MELENA
NERVOUSNESS
PAIN, ABDOMEN
PALLOR
PALLOR, MUCOUS MEMBRAN
POLYDIPSIA
POLYPNEA
PR-SM INTEST, LESION(S
PRURITIS
STIFFNESS
SWELLING, HEAD/FACE
TREMBLING
URTICARIA
VOCALIZATION
VOMITING
WEAKNESS
WEIGHT LOSS
 

#6 REPORT DATE: 5/02/05
 
Report Title "PARENTERAL, DOG" (injection)
 
Reviews:    1
Treated:     1
Reacted:    1
Died:           0
 
Symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
APPLICATION SITE ALOPECIA  (100%)
APPLICATION SITE LESION(S)   (100%)
RASH                                                     (100%)
 

#7 REPORT DATE: 5/02/05
 
Report Title: "Selemectin, UNKNOWN, DOG" (NOTE: presumably the "unknown" title indicates it's not known how the dog got this) 
 
Reviews:    23
Treated:     45
Reacted:    44  (NOTE: as ADE's are filed to report reactions, it is not known how there was 1 dog who allegedly did not have a reaction when treated; possibly the "Arthur Anderson Principles of Accounting were used here or the dog "took the 5th Amendment and refused to tell)
Died:             7
 
Symptoms/conditions caused by and/or associated with REVOLUTION administration:
 
ANOREXIA
APPLICATION SITE ERYTHEMA
ATAXIA
BEHAVIOR DISORDER
BLINDNESS
CNS DISORDER
CONGESTION, SKIN
CONVULSION(S)
DIARRHEA
DIARRHEA, WATERY
EPIPHORA
GASTRITIS
ILL
INEFFECT, EAR MITES
INEFFECT, ECTOPARASITE
INEFFECT, FLEAS
LAB/BLOOD:
    P LO, BLD
LIVER DISORDER
PRURITIS
REFLEX(ES) ABN
SKIN:
    INFLAM, SKIN
    LESION(S), SKIN
    SKIN DISORDER
    STOOL, MUCOID
    VESICLE(S)/BULLAE, SKI
VOMITING
WEAKNESS
 



May my beloved partner ROMI rest in peace  - no matter wherever her bits and pieces/frozen carcass may be held hostage.

                                      

[what's in YOUR "urn" ?]

http://www.thesqueakywheel.com/complaints/complaint5611.cfm

 
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