ROMI's WEBSITE
 
You are at the
 
 PRIMOR
(sulfadimethoxine)
 
page, which is devoted to providing information on a common veterinary antibiotic.  The first section lists the symptoms/conditions caused by and/or associated with its administration per the FDA/CVM's ADE [adverse drug event] reports, which is estimated to reflect LESS than 10% of actual "events" as it is strictly VOLUNTARY and NOT mandatory for veterinarians to report these occurrences. This information was taken directly from the FDA/CVM ADE reports and the only changes that have been made are the listings of symptoms and conditions is that they have been put into alphabetical order, in some cases "grouping" of conditions with a heading that's underlined, and the addition of medical terminology for your convenience from: MedlinePlus at: http://www2.merriam-webster.com/cgi-bin/mwmednlm
 
NOTE: If you are interested in learning more about how to read laboratory test results, visit: http://home.gci.net/~divs/disease/lab_tests.html#rbc
 
The second section is the information provided on the Internet by a company that SELLS this drug.
 
The music for this page is "Let The Good Times Roll".
 
To return to the main/index page, you may use your "back" browser, or click here: http://rimadyldeath.com/index.html

 
The FDA/CVM ADE REPORT
 
from FDA/CVM at: http://www.fda.gov/cvm/Documents/ade_web_rpts_SZ.pdf
 
FDA/CVM Reports - NOTE:  site address (4/22/05):  
FDA/CVM REPORT dated 4/01/05
 
SULFADIMETHOXINE: ORAL, DOG
 
Reviews:      97    [28.86% reviews/mortality]
Treated:     726   [42.01% treated/reacted]
Reacted:    305   [9.18% reacted/died]
Died:             28
 
SYMPTOMS/CONDITIONS per FDA/CVM ADE [adverse drug event] reports:


ANAPHYLAXIS/TOID - 1 : hypersensitivity (as to foreign proteins or drugs) resulting from sensitization following prior contact with the causative agent
2 : ANAPHYLACTIC SHOCK : an often severe and sometimes fatal systemic reaction in a susceptible individual upon a second exposure to a specific antigen (as wasp venom or penicillin) after previous sensitization that is characterized especially by respiratory symptoms, fainting, itching, and hives
ANEMIA - a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume -- see APLASTIC ANEMIA, HYPERCHROMIC ANEMIA, HYPOCHROMIC ANEMIA, MEGALOBLASTIC ANEMIA, MICROCYTIC ANEMIA, PERNICIOUS ANEMIA, SICKLE-CELL ANEMIA
ANEMIA, AUTOIMMUNE HEM - of, relating to, or caused by antibodies or T cells that attack molecules, cells, or tissues of the organism producing them
ANOREXIA - loss of appetite especially when prolonged
ATAXIA - an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders
BEHAVIOR DISORDER (unspecified)
BITING/CHEWING
BLEEDING:
    BLD, MOUTH/LIP(S)
    BLD, SCLERA
    BLD, URINE
COLLAPSE
CONGESTION (unspecified)
CONFUSION
CONVULSION(S) - an abnormal violent and involuntary contraction or series of contractions of the muscles -- often used in plural <a patient suffering from convulsions
DEHYDRATION - the process of dehydrating ; especially : an abnormal depletion of body fluids
DEPRESSION/LETHARGY
DIARRHEA
DIARRHEA, BLOODY
DISTRESS, RESP
EDEMA, HEAD/FACE
EYES:
    BLD, SCLERA
    EDEMA, CORNEA(S)
    EDEMA, EYE(S)/LID(S)
    KERATOCONJUNCTIVITIS S - combined inflammation of the cornea and conjunctiva
    OPACITY, CORNEA(S)
    SWELLING, EYE(S)/LID(S
FEVER, BODY
FROTH, MOUTH/LIP(S)
HEAD TILT
HEART:
    PRESSURE LO, BLD
HYPERACTIVITY
HYPERSALIVATION
ICTERUS, BODY JAUNDICE 1 : a yellowish pigmentation of the skin, tissues, and certain body fluids caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states) -- called also icterus
2 : any disease or abnormal condition (as hepatitis A or leptospirosis) that is characterized by jaundice -- called also icterus
ILL
INEFFECT, COCCIDIA - a large order of schizogonic telosporidian sporozoans typically parasites of the digestive epithelium of vertebrates and higher invertebrates and including several forms of great economic importance
LAB TESTS/BLOOD:
    ALBUMIN LO, BLD
    ALK PHOS HI, BLD
    BILIRUBIN(TOT) HI, BLD
    GLOBULIN LO, BLD
    HEMOGLOBIN, URINE
    PLATELETS LO, BLD
    RETICULOCYTES HI, BLD
    SGPT/ALT HI, BLD
    WBC HI, BLD
    WBC LO, BLD
LAB TESTS/URINE:
    BLD, URINE
    CYSTITIS
LAMENESS
LIVER DISORDER
MELENA - the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum
PAIN (unspecified)
PAIN, ABDOMEN
PALLOR (site unspecified)
PALLOR, MUCOUS MEMBRAN
PARESIS - slight or partial paralysis
PD-ODOR, ABN
PD-TABLET(S), ABN
PRURITIS - no such word: PRURITUS: localized or generalized itching due to irritation of sensory nerve endings from organic or psychogenic causes : ITCH
SHOCK - 1 : a sudden or violent disturbance in the mental or emotional faculties; 2 : a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery <the patient was admitted to the hospital in shock>; 3 : sudden stimulation of the nerves or convulsive contraction of the muscles accompanied by a feeling of concussion that is caused by the discharge through the animal body of electricity from a charged source -- compare
SKIN:
    CONGESTION, SKIN
    ERUPTION(S)
    RASH
    SKIN, CRUST(S)
    SKIN, NECROSIS
    VESICLE(S)/BULLAE, SKI - 1 a : a membranous and usually fluid-filled pouch (as a cyst, vacuole, or cell) in a plant or animal b : SYNAPTIC VESICLE; 2 : a small abnormal elevation of the outer layer of skin enclosing a watery liquid : BLISTER; 3 : a pocket of embryonic tissue that is the beginning of an organ
STAGGERING
SWELLING, HEAD/FACE
SWELLING, JOINT(S)
SWELLING, NECK
TEETH, ABN
TREMBLING
ULCER(S), MOUTH/LIP(S)
URTICARIA - HIVES : an allergic disorder marked by raised edematous patches of skin or mucous membrane and usually by intense itching and caused by contact with a specific precipitating factor (as a food, drug, or inhalant) either externally or internally -- called also urtic
VOMITING
WEAKNESS
 
SULFADIMETHOXINE:  PARENTERAL, DOG (injection, not tablet/oral)
 
FDA/CVM REPORT DATED: April 1, 2005

Reviews:   4  [25% reviews/mortality]
Treated:   4  [100% treated/reacted]
Reacted:  4  [25% reacted/mortality]
Died:         1
 
SYMPTOMS/SIGNS:
 
ENLARGEMENT(S) (unspecified)
INJ SITE ABSCESS
PTT PROLONGED, BLD
SEDATION
- 1 : the inducing of a relaxed easy state especially by the use of sedatives; 2 : a state resulting from sedation
 
 
PRIMOR (sulfadimethoxine)
 
from: http://www.1800petmeds.com/pdetail.asp?SK=10215&SP=dog&WT=&MG=240&PT=
 
Generic Name: Sulfadimethoxine/Ormetoprim

Brand Name(s):  Primor Tablets (Pfizer Animal Health)

What is this medication used for: Primor, a potentiated sulfa drug, is used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria.
 
Availability:  Primor is a prescription medication available as scored tablets.

How this medicine should be used:  An initial starting dose of 25mg/lb on the first day of treatment is followed by a dose of 12.5mg/lb given once a day. Treatment should continue for 2 days after symptoms disappear, however, treatment should not extend past 21 consecutive days.

What are the side effects: Side effects associated with this medication may include polyarthritis, hives, facial swelling, fever, hemolytic anemia, increased thirst and urination, vomiting, diarrhea, and loss of appetite. In rare instances, behavioral changes, seizures, aggression and hyper-excitability have occurred.

What special precautions are there: Do not use in dogs allergic to this medication or other sulfonamides. Do not use in dogs with liver damage or blood dyscrasias. Dogs must maintain adequate fluid intake. The safety in breeding dogs has not been established.

In the event of an overdose: Contact your veterinarian or veterinary emergency room.

How should I store this medication: Keep this medication in the container it came in, tightly closed. Store tablets at room temperature, away from excess heat, light and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep this medication out of the reach of children and pets.

This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.

The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.



May my beloved partner ROMI rest in peace  - no matter wherever her bits and pieces/frozen carcass may be held hostage.

                                      

[what's in YOUR "urn" ?]

http://www.thesqueakywheel.com/complaints/complaint5611.cfm

 
Copyright: 2004 Ginger Sanchez. All Rights Reserved.
This Website Built and Hosted for Free at
Bravenet.com