page, which is devoted to providing information on a common veterinary antibiotic. The first section lists the symptoms/conditions caused by and/or associated with its administration per the FDA/CVM's ADE [adverse drug event] reports, which is estimated to reflect LESS than 10% of actual "events" as it is strictly VOLUNTARY and NOT mandatory for veterinarians to report these occurrences. This information was taken directly from the FDA/CVM ADE reports and the only changes that have been made are the listings of symptoms and conditions is that they have been put into alphabetical order, in some cases "grouping" of conditions with a heading that's underlined, and the addition of medical terminology for your convenience from: MedlinePlus at: http://www2.merriam-webster.com/cgi-bin/mwmednlm
SYMPTOMS/CONDITIONS per FDA/CVM ADE [adverse drug event] reports:
ANAPHYLAXIS/TOID - 1 : hypersensitivity (as to foreign proteins or drugs) resulting from sensitization following prior contact with the causative agent 2: ANAPHYLACTIC SHOCK : an often severe and sometimes fatal systemic reaction in a susceptible individual upon a second exposure to a specific antigen (as wasp venom or penicillin) after previous sensitization that is characterized especially by respiratory symptoms, fainting, itching, and hives ANEMIA - a condition in which the blood is deficient in red blood cells, in hemoglobin, or in total volume -- see APLASTIC ANEMIA,HYPERCHROMIC ANEMIA,HYPOCHROMIC ANEMIA,MEGALOBLASTIC ANEMIA,MICROCYTIC ANEMIA,PERNICIOUS ANEMIA,SICKLE-CELL ANEMIA ANEMIA, AUTOIMMUNE HEM - of, relating to, or caused by antibodies or T cells that attack molecules, cells, or tissues of the organism producing them ANOREXIA - loss of appetite especially when prolonged ATAXIA - an inability to coordinate voluntary muscular movements that is symptomatic of some nervous disorders BEHAVIOR DISORDER (unspecified) BITING/CHEWING BLEEDING:
BLD, MOUTH/LIP(S) BLD, SCLERA BLD, URINE COLLAPSE CONGESTION (unspecified) CONFUSION CONVULSION(S) - an abnormal violent and involuntary contraction or series of contractions of the muscles -- often used in plural <a patient suffering from convulsions DEHYDRATION - the process of dehydrating ; especially: an abnormal depletion of body fluids DEPRESSION/LETHARGY DIARRHEA DIARRHEA, BLOODY DISTRESS, RESP EDEMA, HEAD/FACE EYES:
BLD, SCLERA EDEMA, CORNEA(S) EDEMA, EYE(S)/LID(S) KERATOCONJUNCTIVITIS S - combined inflammation of the cornea and conjunctiva OPACITY, CORNEA(S) SWELLING, EYE(S)/LID(S FEVER, BODY FROTH, MOUTH/LIP(S) HEAD TILT HEART:
PRESSURE LO, BLD HYPERACTIVITY HYPERSALIVATION ICTERUS, BODY - JAUNDICE 1 : a yellowish pigmentation of the skin, tissues, and certain body fluids caused by the deposition of bile pigments that follows interference with normal production and discharge of bile (as in certain liver diseases) or excessive breakdown of red blood cells (as after internal hemorrhage or in various hemolytic states) -- called also icterus 2: any disease or abnormal condition (as hepatitis A or leptospirosis) that is characterized by jaundice -- called also icterus ILL INEFFECT, COCCIDIA - a large order of schizogonic telosporidian sporozoans typically parasites of the digestive epithelium of vertebrates and higher invertebrates and including several forms of great economic importance LAB TESTS/BLOOD:
BLD, URINE CYSTITIS LAMENESS LIVER DISORDER MELENA - the passage of dark tarry stools containing decomposing blood that is usually an indication of bleeding in the upper part of the alimentary canal and especially the esophagus, stomach, and duodenum PAIN (unspecified) PAIN, ABDOMEN PALLOR (site unspecified) PALLOR, MUCOUS MEMBRAN PARESIS - slight or partial paralysis PD-ODOR, ABN PD-TABLET(S), ABN PRURITIS - no such word: PRURITUS: localized or generalized itching due to irritation of sensory nerve endings from organic or psychogenic causes : ITCH SHOCK - 1 : a sudden or violent disturbance in the mental or emotional faculties; 2: a state of profound depression of the vital processes of the body that is characterized by pallor, rapid but weak pulse, rapid and shallow respiration, reduced total blood volume, and low blood pressure and that is caused usually by severe especially crushing injuries, hemorrhage, burns, or major surgery <the patient was admitted to the hospital in shock>; 3: sudden stimulation of the nerves or convulsive contraction of the muscles accompanied by a feeling of concussion that is caused by the discharge through the animal body of electricity from a charged source -- compare SKIN:
CONGESTION, SKIN ERUPTION(S) RASH SKIN, CRUST(S) SKIN, NECROSIS VESICLE(S)/BULLAE, SKI - 1 a : a membranous and usually fluid-filled pouch (as a cyst, vacuole, or cell) in a plant or animal b: SYNAPTIC VESICLE; 2: a small abnormal elevation of the outer layer of skin enclosing a watery liquid : BLISTER; 3: a pocket of embryonic tissue that is the beginning of an organ STAGGERING SWELLING, HEAD/FACE SWELLING, JOINT(S) SWELLING, NECK TEETH, ABN TREMBLING ULCER(S), MOUTH/LIP(S) URTICARIA - HIVES : an allergic disorder marked by raised edematous patches of skin or mucous membrane and usually by intense itching and caused by contact with a specific precipitating factor (as a food, drug, or inhalant) either externally or internally -- called also urtic VOMITING WEAKNESS
SULFADIMETHOXINE: PARENTERAL, DOG (injection, not tablet/oral)
ENLARGEMENT(S) (unspecified) INJ SITE ABSCESS PTT PROLONGED, BLD SEDATION - 1 : the inducing of a relaxed easy state especially by the use of sedatives; 2: a state resulting from sedation
What is this medication used for: Primor, a potentiated sulfa drug, is used in dogs for the treatment of skin and soft tissue infections (wounds and abscesses), and urinary tract infections caused by susceptible bacteria.
Availability: Primor is a prescription medication available as scored tablets.
How this medicine should be used: An initial starting dose of 25mg/lb on the first day of treatment is followed by a dose of 12.5mg/lb given once a day. Treatment should continue for 2 days after symptoms disappear, however, treatment should not extend past 21 consecutive days.
What are the side effects: Side effects associated with this medication may include polyarthritis, hives, facial swelling, fever, hemolytic anemia, increased thirst and urination, vomiting, diarrhea, and loss of appetite. In rare instances, behavioral changes, seizures, aggression and hyper-excitability have occurred.
What special precautions are there: Do not use in dogs allergic to this medication or other sulfonamides. Do not use in dogs with liver damage or blood dyscrasias. Dogs must maintain adequate fluid intake. The safety in breeding dogs has not been established.
In the event of an overdose: Contact your veterinarian or veterinary emergency room.
How should I store this medication: Keep this medication in the container it came in, tightly closed. Store tablets at room temperature, away from excess heat, light and moisture. Do not store in the bathroom. Throw away any medication that is outdated or no longer needed. Keep this medication out of the reach of children and pets.
This information sheet is for educational purposes only and is intended to be a supplement to, and not a substitute for, the expertise and professional judgment of your veterinarian. The information is NOT to be used for diagnosis or treatment of your pet. You should always consult your own veterinarian for specific advice concerning the treatment of your pet.
The information is not intended to cover all possible uses, directions, precautions, warnings, allergic reactions, drug interactions or adverse effects, nor should it be construed to indicate that use of a particular drug is safe, appropriate or effective for your pet. It is not a substitute for a veterinary exam, and it does not replace the need for services provided by your veterinarian.
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